Hyperparathyroidism classification

Different causes and features of hyperparathyroidism - raised parathormone (PTH).

 renal  endocrinology  MRCP

pathologyHyperfunction of parathyroid cells due to hyperplasia, adenoma or carcinoma.Physiological stimulation of parathyroid in response to hypocalcaemia.Following long term physiological stimulation leading to hyperplasia.
associationsMay be associated with multiple endocrine neoplasia.Usually due to chronic renal failure or other causes of Vitamin D deficiency.Seen in chronic renal failure.
serum calciumhighlow / normalhigh
serum phosphatelow / normalhighhigh
managementUsually surgery if symptomatic. Cincacalcet can be considered in those not fit for surgery.Treatment of underlying cause.Usually cinacalcet or surgery in those that don't respond.
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NICE have issued guidance for the use of cinacalcet in what they call refractory secondary hyperparathyroidism which is classified as tertiary hyperparathyroidism in this tblable. http://www.nice.org.uk/TA117


Renal tubular acidosis types | Hyponatraemia | Oligomenorrhoea and amenorrhoea | Renin-angiotensin-aldosterone system | Jaundice | Granulomatous mycobacterial infections of the skin | Endocarditis | Cutaneous infestations | Eponymous cardiac murmurs | Inflammatory bowel disease | Emphysema | Motor defects | Valvular heart disease | Familial hyperlipidaemias |