Renal tubular acidosis types

Features of different types of renal tubular acidosis

 renal  metabolic  MRCP

Type 1 RTAType 2 RTAType 4 RTA
LocationDistal tubulesProximal tubulesAdrenal
Acidosis degreeYes (severe)YesMild when present
PathophysiologyFailure of H+ secretion by the alpha intercalated cellsFailed bicarbonate reabsorption from the urine by the proximal tubular cellsDeficiency of aldosterone, or a resistance to its effects, (hypoaldosteronism or pseudohypoaldosteronism)
RadiologyNephrocalcinosisOsteomalacia or rickets
random card | random quiz


Hyperparathyroidism classification | Hyponatraemia | Cutaneous infestations | Eponymous cardiac murmurs | Inflammatory bowel disease | Oligomenorrhoea and amenorrhoea | Emphysema | Motor defects | Valvular heart disease | Familial hyperlipidaemias | Renin-angiotensin-aldosterone system | Jaundice | Granulomatous mycobacterial infections of the skin | Endocarditis |